Table 5.
miRNAs associated with skin lipids.
| miRNA | Target Molecule | Related Skin Condition | Action Mechanism of miRNA | Reference |
|---|---|---|---|---|
| miR-185-5p ↑ | ALOX12B | Upregulated by p-ΔNp63, resulting in reduced ALOX12B activity. | [117] | |
| miR-203 ↑ | Upregulated by oleic acid, promoting keratinocyte differentiation | [20] | ||
| miR-203 ↑ | Upregulated by linoleic acid, stimulating keratinocyte differentiation | [118] | ||
| miR-574-3p ↑ | ||||
| miR-21-3p ↑ | SMAD7 | UV exposure | Upregulated in a PPARβ/δ-dependent manner Besides regulatory role in immune and inflammatory responses, miR-213p can downregulate caspase-14 expression. (--Arrangement was changed as a center alignment array) |
[119] |
↑: upregulation.