Figure 1.
Excitatory amino acid carrier 1 (EAAC1) is expressed in immature neurons as well as mature neurons. (A–C) Immunofluorescence images representing the expression of EAAC1- (A) and MAP2-immunopositive cells (B) and EAAC1/MAP2 double-positive cells (C) in the hippocampal CA1 of wild-type (WT) mice (3–5 months old; weight 25–35 g). Scale bar = 5 µm. (D–G) Double-label confocal micrographs of EAAC1 (green) and doublecortin (DCX) (red) in the hippocampal dentate gyrus (DG). Scale bar = 20 µm. (E–G) Higher magnification of the white box in D showing the expression of EAAC1- (E), DCX-immunopositive cells (F), and EAAC1/DCX double-positive cells (G) in the subgranular zone/glutamate-cysteine ligase (SGZ/GCL) of DG. Scale bar = 5 µm.