. 2020 Aug 9;21(16):5707. doi: 10.3390/ijms21165707

Table 1.

Inhibitory activity of K11777 against SARS-CoV replication in Vero 76 cells.

Compound	SARS-CoV	CPE Inhibition			NR Assay			Virus Yield Reduction
Compound	SARS-CoV	EC₅₀ (µM)	CC₅₀ (µM)	SI	EC₅₀ (µM)	CC₅₀ (µM)	SI	EC₉₀ (µM)
K11777	Urbani	<0.05	>106.6	>2111	<0.52	>100	>193	0.35
K11777	Toronto-2	<0.05	85.2	>1704	<0.35	52.7	>151	1.04