Table 1.
The ARIC-SHHS participant characteristics by OSA severity (n=1525)
| Characteristics | OSA Severity | |||
|---|---|---|---|---|
| Normal: AHI<5, n=776 | Mild: AHI=5 to <15, n=452 | Moderate: AHI=15 to <30, n=197 | Severe: AHI≥30, n=100 | |
| Demographics | ||||
| Baseline age, yr, mean ± SD | 61.7±5.4 | 63.2±5.2 | 63.3±5.4 | 63.1±5.1 |
| Women, n (%) | 505 (65.1) | 199 (44.0) | 60 (30.5) | 35 (35.0) |
| Education level, n (%) | ||||
| Less than high school | 69 (8.9) | 54 (12.0) | 27 (13.7) | 9 (9.0) |
| High school graduate | 372 (47.9) | 208 (46.0) | 85 (43.1) | 47 (47.0) |
| More than high school graduate | 335 (43.2) | 190 (42.0) | 85 (43.2) | 44 (44.0) |
| Lifestyle behavioral characteristics | ||||
| Smoking, n (%) | ||||
| Current | 107 (13.8) | 31 (6.9) | 16 (8.1) | 9 (9.0) |
| Former | 340 (43.8) | 239 (52.9) | 106 (53.8) | 54 (54.0) |
| Never | 329 (42.4) | 182 (40.3) | 75 (38.1) | 37 (37.0) |
| Alcohol consumption, n (%) | ||||
| Current | 542 (69.9) | 313 (69.3) | 123 (62.4) | 64 (64.0) |
| Former | 146 (18.8) | 100 (22.1) | 51 (25.9) | 23 (23.0) |
| Never | 88 (11.3) | 39 (8.6) | 23 (11.7) | 13 (13.0) |
| Physical activity sport index, mean ± SD | 2.7±0.8 | 2.7±0.8 | 2.6±0.7 | 2.4±0.7 |
| Health status characteristics | ||||
| BMI, kg/m2, mean ± SD | 27.0±4.3 | 29.1±4.8 | 31.1±5.5 | 33.8±5.5 |
| hsCRP, mg/L, mean ± SD | 3.7±5.1 | 4.1±6.6 | 3.9±4.9 | 4.8±4.4 |
| Prevalent diabetes, n (%) | 61 (7.9) | 69 (15.3) | 28 (14.2) | 20 (20.0) |
| Systolic BP, mm Hg, mean ± SD | 123.3±17.0 | 127.7±18.6 | 126.2±17.6 | 130.1±16.9 |
| Diastolic BP, mm Hg, mean ± SD | 69.7±9.1 | 71.5±9.8 | 71.3±9.1 | 73.4±10.2 |
| Antihypertensive medication use, n (%) | 192 (24.7) | 124 (27.4) | 66 (33.5) | 41 (41.0) |
| Prevalent CHD, n (%) | 56 (7.2) | 34 (7.5) | 25 (12.7) | 9 (9.0) |
| eGFR, ml/min per 1.73 m2, mean ± SD | 90.4±13.6 | 89.5±15.3 | 88.3±13.2 | 85.5±13.3 |
| Sleep characteristics | ||||
| Arousal index, average no. per night, mean ± SD | 15.6±7.2 | 19.4±8.1 | 23.4±8.7 | 35.7±15.1 |
| Sleep efficiency, mean ± SD | 85.0±8.6 | 83.5±9.3 | 82.2±9.4 | 81.8±10.8 |
| Self-reported poor sleep quality, n (%) | 322 (41.5) | 196 (43.4) | 85 (43.1) | 42 (42.0) |
| Habitual sleep duration, average hours per night, mean ± SD | 7.3±1.1 | 7.24±1.0 | 7.24±1.1 | 7.11±1.1 |
hsCRP, high-sensitivity C-reactive protein.