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Secretin stimulates acute urine alkalization in mice. (A) Photographic image of the in vivo experimental setup. (B) Two original pHu traces are shown, indicating a prompt urine alkalization after application of 400 pg/g body wt (i.p.) secretin (red) and no effect in the control injected mouse (black). (C) Dose response relationship of the secretin effect on pHu, (n=4–7).
