Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 11;21(16):5758. doi: 10.3390/ijms21165758

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Schematic representation of the main epigenetic mechanisms involved in inflammasome activation. DNA methylation, histones post-translational modifications (PTMs) and microRNA-based regulation exert epigenetic control on the level of inflammasome activity, whose dysregulation may result in the development of inflammasome-related diseases. DNMT, DNA methyltransferases; HAT, histone deacetylases; HDAC, histone deacetylases; HMT, histone methyltransferases; HDM, histone demethylases; ASC, apoptosis-associated speck-like protein containing a CARD; NLR, NOD-like receptor and CAPS, cryopyrin-associated periodic syndromes; DSS, dextran sulfate sodium.