Figure 1.

Flow chart showing the strategy for the assembly of LL-100 panel. Data on, and experience with, 744 cell lines in the lab were used to identify features which were considered exclusion criteria versus eligibility criteria. Exclusion criteria: difficult growth, cross-contamination, sister cell lines or subclones, or controversial cell lines including non-malignant Epstein–Barr-virus transformed B-lymphoblastoid cell lines—versus eligibility criteria: vigorous/robust proliferation, public availability, representative for a given entity, well-characterized and comprehensively annotated and classic/reference cell lines.