CTLA-4 | T-lymphocyte-associated protein 4 |
PD-1 | Programmed cell death protein 1 |
ICIs | Immune checkpoint inhibitors |
irAEs | Immune related adverse events |
NirAEs | Neurological immune-related adverse events |
CNS | Central nervous system |
Tregs | Regulatory T-cells |
APCs | Antigen-presenting cells |
PNS | Paraneoplastic syndrome |
NMDAR | N-methyl-D-aspartate receptor |
ES | Epitope spreading |
NSCLC | Non-small cell lung cancer |
Mab | Monoclonal antibodies |