Table 1.
Patient clinical and biological characteristics at admission to the emergency department in the overall study population
| Characteristics | N | Values |
|---|---|---|
| Age, years (mean ± SD) | 243 | 63.9 ± 16.2 |
| Male sex | 243 | 155 (63.8) |
| Body mass index, kg/m2 (mean ± SD) | 200 | 28.0 ± 6.1 |
| Chronic medical illness | ||
| Diabetes | 243 | 56 (23.0) |
| Hypertension | 243 | 118 (48.6) |
| Chronic pulmonary disease | 243 | 38 (15.6) |
| Cardiopathy | 243 | 36 (14.8) |
| Myocardial infarction | 243 | 22 (9.1) |
| Stroke | 243 | 22 (9.1) |
| Hepatopathy | 243 | 5 (2.1) |
| Chronic renal failure | 243 | 17 (7.0) |
| Active cancer | 243 | 23 (9.5) |
| Immunocompromised | 242 | 11 (4.5) |
| Number of medical illness | 243 | |
| None | 79 (32.5) | |
| One | 65 (26.8) | |
| More than one medical illness | 99 (40.7) | |
| Illness characteristics | 243 | |
| Time from illness onset to admission, days | 8 (5‐11) | |
| Admission type | 243 | |
| Emergency department | 158 (65.0) | |
| Ward | 10 (4.1) | |
| ICU | 75 (30.9) | |
| Severity of respiratory illness at admission | ||
| Respiratory rate/min (mean SD) | 236 | 24.0 ± 5.9 |
| PaO2/FiO2 ratio (mmHg) | 236 | 357 (252‐448) |
| Oxygen requirement at admission | ||
| No oxygen | 243 | 74 (30.5) |
| Supplemental oxygen | 102 (42) | |
| Non‐invasive ventilation or high flow oxygenation | 20 (8.2) | |
| Invasive mechanical ventilation | 47 (19.3) | |
| Biological data | ||
| ABO blood group | 192 | |
| A | 192 | 85 (44.3) |
| AB | 11 (5.7) | |
| B | 19 (9.9) | |
| O | 77 (40.1) | |
| Leucocytes/mm3(mean ± SD) | 229 | 181 |
| Neutrophils/mm3 | 7674 ± 3749 | 5000 (3700‐7000) |
| Lymphocytes/mm3 (mean ± SD) | 182 | 1060 ± 611 |
| Monocytes/mm3 | 182 | 400 (300‐700) |
| Platelets, G/L (mean ± SD) | 238 | 228 ± 113 |
| Creatinine, mg/L | 227 | 8 (7‐11) |
| Lactate dehydrogenase, IU/L | 199 | 377 (286‐479) |
| Troponin, ng/L | 204 | 15.0 (7.5‐25.5) |
| CRP, mg/L | 227 | 69 (31‐126) |
| aPTTr | 211 | 1.13 (1.03‐1.23) |
| PTr | 211 | 1.10 (1.04‐1.16) |
| D‐dimers, µg/mL | 227 | 1.00 (0.70‐1.80) |
| Fibrinogen, g/L (mean ± SD) | 227 | 6.1 ± 1.6 |
| FVIII, IU/dL (mean ± SD) | 210 | 241 ± 96 |
| VWF:Ag, IU/dL (mean ± SD) | 212 | 361 ± 128 |
| FVIII/VWF:Ag ratio (mean ± SD) | 210 | 0.72 ± 0.27 |
Note
Values are number (%) or median (interquartile range) unless otherwise as indicated.
Abbreviations: aPTTr, activated partial thromboplastin time ratio; FVIII, factor VIII; ICU, intensive care unit; PTr, prothrombin time ratio; SD, standard deviation; VWF, von Willebrand factor.