AGO2	Argonaute 2
ApoB	Apolipoprotein B
ASOs	Antisense oligonucleotides
BBB	Blood-brain barrier
C6-Cer	C6-ceramide
CML	Chronic myeloid leukemia
CNS	Central nervous system
CSCs	Cancer stem cells
CSF	Cerebrospinal fluid
CTX	Chlorotoxin
DAGs	Diacylglycerols
DSPC	1,2-distearoyl-sn-glycero-3-phosphocholine
dsRNA	Double-stranded RNA
DXR	Doxorubicin
EBOV	Ebola virus
ERT	Enzyme replacement therapy
FD	Fabry disease
GAGs	Glycosaminoglycans
GD	Gaucher disease
GBM	Glioblastoma
gSRT	Genetic substrate reduction therapy
hATTR	Hereditary TTR-mediated amyloidosis
HBV	Hepatitis B virus
HF	Hemorrhagic fever
HIV	Human immunodeficiency virus
HMEC-1	Angiogenic endothelial cells
HS	Heparan sulphate
ICV	Intracerebroventricular
iPSCs	Induced pluripotent stem cells
IT	Intrathecal
IV	Intravenous
KSP	Kinesin spindle protein
LNPs	Lipid nanoparticles
LDL	Low-density lipoprotein
LSDs	Lysosomal storage disorders
miRNA	microRNA
MLD	Metachromatic Leukodystrophy
MPSs	Mucopolysaccharidoses
mRNA	messenger RNA
NCAM	Neural cell adhesion molecule
NCLs	Neuronal Ceroid Lipofuscinoses
nACh	Nicotinic acetylcholine
nAChR	Nicotinic acetylcholine receptor
n-SCC	Non-stem cancer cells
PD	Parkinson’s disease
PLK1	Polo-like kinase 1
PEG	Polyethylene glycol
PEI	Polyethylenimine
PC3	Prostate cancer cells
PKR	Protein kinase receptor
P75NTR	Neurotrophin receptor 75
RDP	Rabies virus derived peptide
RVG	Rabies virus glycoprotein
RVG-9r	Rabies virus peptide derivative
RME	Receptor-mediated endocytosis
rhTPP1	Recombinant human tripeptidyl peptidase 1
RES	Reticuloendothelial system
RNAi	RNA interference
RISC	RNA-induced silencing complex
shRNA	Short hairpin RNA
siRNAs	small interfering RNAs
SNALP	Stable nucleic acid lipid particle
SRT	Substrate reduction therapy
TLRs	Toll-like receptors
Trf	Transferrin
TrfR	Transferrin receptor
TTR	Transthyretin
T1/2	Elimination/circulation half-time
U.S. FDA	United States Food and drug administration
VLDL	Very-low-density lipoprotein
ZEBOV	Zaire species of EBOV
3’-UTR	3’ untranslated region