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. 2020 Sep 1;146(3):e20200567. doi: 10.1542/peds.2020-0567

TABLE 1.

Classification of Infants With NAS-Related ICD-10-CM Codes by Florida NAS Case Definition

Classification of NAS P96.1 (n = 128) P04.49 (n = 68) P96.1 and P04.49 (n = 7) Total Cases (n = 203)
Recent maternal opioid, benzodiazepine, or barbiturate usea (A) 126 (98.4) 30 (44.1) 7 (100) 163 (80.3)
Clinical signsb (B) 127 (99.2) 16 (23.5) 7 (100) 150 (73.9)
Severity of signs: hospitalization >3 daysc (C) 123 (96.1) 27 (39.7) 7 (100) 157 (77.3)
Confirmed NAS (A, B, and C) 122 (95.3) 9 (13.2) 7 (100) 138 (68.0)
Suspect NAS (B and C) 1 (0.8) 2 (2.9) 0 (0) 3 (1.5)
Monitor for NASd (A; A and B) 4 (3.1) 21 (30.9) 0 (0) 25 (12.3)
No NAS 1 (0.8) 36 (52.9) 0 (0) 37 (18.2)

Data are presented as n (%). A, Recent maternal opioid, benzodiazepine, or barbiturate use; B, Clinical signs; C, Severity of signs: hospitalization >3 days.

a

Opioid, benzodiazepine, or barbiturate use during pregnancy was identified as reported by the patient and/or MD, a positive mother or infant drug screen result, and or a reported drug prescription.

b

Presence of ≥1 clinical signs associated with NAS.

c

Birth hospitalization >3 days for the treatment of withdrawal.

d

Monitor for NAS included presence of A only or A and B.