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. 2021 Feb 1;57(2):242–247. doi: 10.1002/uog.22178

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© 2020 International Society of Ultrasound in Obstetrics and Gynecology

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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UOG-22178-FIG-0002-c — Expression of SARS‐CoV‐2‐specific receptor, angiotensin‐converting enzyme 2 (ACE2), in fetal brain (a), heart (b), eye (c) and olfactory mucosa (d), as detected by immunohistochemistry using anti‐ACE2 antibodies. (a) Fetal brain at 20 + 1 weeks. Top left: light microscopy (original magnification, ×100) revealed no ACE2 expression in frontal cortex. Top right: light microscopy (×400) revealed no ACE2 expression in brain ependyma. Bottom left and right: light microscopy (×40 and ×400) showed ACE2 expression in choroid plexus. (b) Heart at 38 + 1 weeks. Light microscopy (×400) showed no expression of ACE2 in heart or coronary artery. (c) Eye at 38 + 1 weeks. Light microscopy (×400) showed ACE2 expression in apical membrane in cornea and bulbar conjunctiva. (d) Olfactory mucosa at 29 + 4 weeks. Light microscopy (×400, ×200) showed staining in Bowman's gland.