Table 1.
Demographics and clinical characteristics of the patients
| Variable | All (n = 792) | Survivors (n = 724) | Nonsurvivors (n = 68) | P value |
|---|---|---|---|---|
| Age, y | 55.0 (36.0‐68.0) | 52.0 (34.5‐65.0) | 70.0 (68.0‐77.5) | <.001 |
| Men | 432 (55%) | 398 (55%) | 34 (50%) | .431 |
| Wuhan exposure | 92 (12%) | 72 (10%) | 20 (29%) | <.001 |
| Comorbidities | ||||
| Hypertension | 215 (27%) | 181 (25%) | 34 (50%) | <.001 |
| Diabetes | 142 (18%) | 116 (16%) | 26 (38%) | <.001 |
| COPD | 19 (2%) | 14 (2%) | 5 (7%) | .005 |
| Chronic kidney disease | 26 (3%) | 21 (3%) | 5 (7%) | .049 |
| Initial symptoms | ||||
| Fever | 623 (79%) | 564 (78%) | 59 (87%) | .088 |
| Cough | 588 (74%) | 536 (74%) | 52 (76%) | .660 |
| Expectoration | 146 (18%) | 130 (18%) | 16 (24%) | .257 |
| Myalgia or fatigue | 254 (32%) | 224 (31%) | 30 (44%) | .026 |
| Shortness of breath | 49 (6%) | 43 (6%) | 6 (9%) | .345 |
| Diarrhea | 56 (7%) | 51 (7%) | 5 (7%) | .924 |
| Time from illness onset to first hospital admission, d | 4.0 (2.7‐6.0) | 4.0 (2.0‐6.1) | 4.0 (3.0‐5.0) | .909 |
| SOFA score (points) | 1.5 (1.0‐2.5) | 1.0 (1.0‐2.0) | 3.0 (2.0‐4.0) | <.001 |
| Complications | ||||
| ARDS | 104 (13%) | 43 (6%) | 61 (90%) | <.001 |
| Respiratory failure | 252 (32%) | 188 (26%) | 64 (94%) | <.001 |
| Sepsis | 321 (41%) | 253 (35%) | 68 (100%) | <.001 |
| Sepsis shock | 39 (5%) | 0 (0) | 39 (57%) | <.001 |
| Secondary infection | 35 (4%) | 7 (1%) | 28 (41%) | <.001 |
| Acute cardiac injury | 40 (5%) | 7 (1%) | 33 (49%) | <.001 |
| Acute kidney injury | 46 (6%) | 14 (2%) | 32 (47%) | <.001 |
| Treatment | ||||
| Antiviral therapy | 654 (83%) | 623 (86%) | 21 (31%) | <.001 |
| Corticosteroids | 143 (18%) | 116 (16%) | 27 (40%) | <.001 |
| Antibiotic therapy | 715 (90%) | 651 (90%) | 64 (94%) | .264 |
| High‐flow oxygen therapy | 90 (11%) | 51 (7%) | 39 (57%) | <.001 |
| ICU admission | 94 (12%) | 44 (6%) | 50 (74%) | <.001 |
| Noninvasive ventilation | 44 (6%) | 14 (2%) | 30 (44%) | <.001 |
| Invasive mechanical ventilation | 47 (6%) | 7 (1%) | 40 (59%) | <.001 |
| Renal replacement therapy | 11 (1%) | 0 (0) | 11 (16%) | <.001 |
| Days from illness onset to death or discharge death or discharge, d | 21.0 (18.0‐24.0) | 22.5 (19.0‐25.0) | 19.0 (16.5‐24.0) | .094 |
Note: Data are expressed as the median (interquartile range) or n (%).
Abbreviations: ARDS, acute respiratory distress syndrome; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; SOFA, Sequential Organ Failure Assessment.