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. 2020 Sep 1;146(3):e20200794. doi: 10.1542/peds.2020-0794

TABLE 2.

Frequency and Relative Risk of Developmental Vulnerability by Maternal Depression Diagnosis Between Child’s Birth and Fifth Birthday (N = 52 103)

Developmental Domain Maternal Depression Diagnosis Between Child’s Birth and Fifth Birthday Relative Risk (95% CI)
Yes (n = 9938) No (n = 42 165)
Vulnerable on Domain, n (%) Vulnerable on Domain, n (%) Unadjusted Adjusteda
≥1 domain 2930 (29.5) 10 297 (24.4) 1.29 (1.23–1.36) 1.17 (1.11–1.23)
Specific domain
 Physical health and well-being 1473 (14.8) 4555 (10.8) 1.44 (1.35–1.53) 1.28 (1.20–1.36)
 Social competence 1312 (13.2) 4098 (9.7) 1.41 (1.32–1.51) 1.28 (1.20–1.38)
 Emotional maturity 1307 (13.2) 4246 (10.1) 1.35 (1.27–1.45) 1.27 (1.18–1.36)
 Language and cognitive development 1175 (11.8) 4171 (9.9) 1.22 (1.14–1.31) 1.07 (1.00–1.15)
 Communication skills and general knowledge 920 (9.3) 3909 (9.3) 1.00 (0.93–1.08) 0.91 (0.83–0.98)
a

Adjusted for maternal characteristics at birth (age at first birth, education, social isolation, marital status, smoking during pregnancy, drug or alcohol use during pregnancy, neighborhood location, and income quintile) and child characteristics at birth (birth order, sex, and gestational age).