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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Am Chem Soc. 2019 Oct 23;141(44):17588–17600. doi: 10.1021/jacs.9b06410

Scheme 1.

Scheme 1.

Synthetic Sequence Leading to the One-Pot Preparation of C3-Symmetric Macrocycles (TC-6, TC-10, TC-18) from the Azide-alkyne Building Block 7 Bearing the Appropriate Alkyl Chain