TABLE 1.
Parvovirus B19 IgM, IgG and DNA viral load in 322 patients with sickle cell disease at enrolment
| Interpretation | IgM | IgG | PCR | Viral load; mean (SD) IU/mL; median (IQR) IU/mL | N |
|---|---|---|---|---|---|
| Never infected | Neg | Neg | Neg | 3.1 (11.3) 0 (0–0) |
144 |
| Old infection, cleared | Neg | Pos | Neg | 13.5 (21.5) 0 (0–31.0) |
29 |
| Recent infection, cleared | Pos | Pos | Neg | 10.5 (18.8) 0 (0–20.3) |
54 |
| Recent infection, cleared | Pos | Neg | Neg | 9.1 (17.8) 0 (0–4.0) |
24 |
| Early recent infection, active | Neg | Neg | Pos | 17 054.3 (71 632.0) 162.1 (95.95.3–685.4) |
21 |
| Recent infection, active | Pos | Pos | Pos | 7595.2 (25 672.3) 540.6 (119.6–1363.5) |
21 |
| Recent infection, active | Pos | Neg | Pos | 22 758.2 (67 814.8) 174.7 (106.5–802.2) |
20 |
| Chronic infection | Neg | Pos | Pos | 12 037.4 (32 004.2) 588.8 (199.4–1396.6) |
9 |
Note: The cutoff for PCR positivity was >0.90 IU/μL in the tested eluate or a viral load in the original sample of >68.00 IU/mL.