Fig. 4.

a Systolic blood pressure in normal mice after IP injection of high-sodium saline or miso supernatant. n = 5 for each. *p < 0.05 high-sodium saline versus miso supernatant. b LF/HF ratio (left) and heart rate (right) in normal mice evaluated via ECG. The LF/HF ratio before the injection was assigned a value of 1.0. n = 9 for each. *p < 0.05, **p < 0.01 high-sodium saline versus miso supernatant. IP, intraperitoneal; LF, low frequency power of heart rate variability; HF, high frequency power of heart rate variability