Fig. 6.

a The constructed transcription factor (TF)-miRNA-mRNA regulatory network. The red round nodes represent upregulated differentially expressed genes (DEGs); the blue round nodes represent downregulated DEGs; the green triangle nodes represent miRNAs; green rhombus nodes represent TF. The gray lines represent the interaction relationship; the red lines represent the activation relationship of TF-mRNA; the blue lines represent the inhibition relationship of TF-mRNA. B and C: The GO function (b) and KEGG pathway (c) enriched by the TF-mRNA