Table 5.
Haplotype pattern of PmMDR1 in Thailand and Myanmar
| Structure | Parasite cytoplasmic side | NBD1 | TMD11 | NBD2 | Thailand % (N) | Myanmar % (N) | Frequency % (N) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Haplotypes | N6I | Y7C | L490I | L1063F | N1248I | T1266S | R1361S | T1406S | A1460S | A1460T | |||
| 1 | N | Y | L | F | N | T | R | T | A | A | 27.45% (14/51) | 0% (0/44) | 14.73% (14/95) |
| 2 | I | Y | L | L | N | T | R | T | A | A | 3.92% (2/51) | 0% (0/44) |
2.10% (2/95) |
| 3 | N | C | L | L | N | T | R | T | A | A | 3.92% (2/51) | 2.27% (1/44) |
3.57% (3/95) |
| 4 | N | Y | L | L | N | S | R | T | A | A | 1.97% (1/51) | 9.10% (4/44) |
5.26% (5/95) |
| 5 | N | C | I | L | N | S | R | T | A | T | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 6 | N | C | L | L | N | S | R | T | S | A |
0% (0/51) |
2.27% (1/44) |
1.05% (1/95) |
| 7 | N | Y | L | L | N | S | R | T | S | A | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 8 | N | Y | L | F | N | T | S | S | A | A | 3.92% (2/51) | 0% (0/44) |
2.10% (2/95) |
| 9 | N | Y | I | L | N | T | R | T | A | A | 0% (0/51) | 6.82% (3/44) |
3.57% (3/95) |
| 10 | N | Y | L | L | I | T | R | T | A | A | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 11 | N | Y | L | L | I | S | R | T | A | A | 0% (0/51) | 6.82% (3/44) |
3.57% (3/95) |
| 12 | N | Y | L | L | I | S | R | S | S | A | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 13 | N | Y | L | L | N | T | R | S | S | A | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 14 | N | Y | L | L | N | T | R | T | A | T | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 15 | N | Y | L | L | N | T | S | T | A | A | 0% (0/51) | 2.27% (1/44) |
1.05% (1/95) |
| 16 | N | Y | L | L | N | T | R | T | A | A | 58.82% (30/51) | 56.82% (25/44) | 58.94% (55/95) |
| Total | 51 | 44 | 100% (95) | ||||||||||
Accession number of reference sequence: LT594631.1