TABLE 4.
Diagnostic agreement of Xpert® Flu/RSV with Allplex™ RP1 by influenza season
| Influenza A | Influenza B | RSV | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Influenza season (n = 412) | Non‐influenza season (n = 502) | Influenza season (n = 412) | Non‐influenza season (n = 502) | Influenza season (n = 412) | Non‐influenza season (n = 502) | |||||||||||||
| Allplex™ RP1 | Allplex™ RP1 | Allplex™ RP1 | Allplex™ RP1 | Allplex™ RP1 | Allplex™ RP1 | |||||||||||||
| Xpert® Flu/RSV | + | − | Total | + | − | Total | + | − | Total | + | − | Total | + | − | Total | + | − | Total |
| + | 40 | 2 | 42 | 37 | 3 | 40 | 9 | 1 | 10 | 5 | 0 | 5 | 11 | 0 | 11 | 31 | 0 | 31 |
| − | 2 | 368 | 370 | 2 | 460 | 462 | 2 | 400 | 402 | 0 | 497 | 497 | 11 | 390 | 401 | 1 | 470 | 471 |
| Total | 42 | 370 | 412 | 39 | 463 | 502 | 11 | 401 | 412 | 5 | 497 | 502 | 22 | 390 | 412 | 32 | 470 | 502 |
| PPA (95% CI) | 95.2 (83.8‐99.4) | 94.9 (82.7‐99.4) | 81.8 (48.2‐97.7) | 100.0 (47.8‐100.0) | 50.0 (28.2‐71.8) | 96.9 (83.8‐99.9) | ||||||||||||
| NPA (95% CI) | 99.5 (98.1‐99.9) | 99.4 (98.1‐99.9) | 99.8 (98.6‐100.0) | 100.0 (99.3‐100.0) | 100.0 (99.1‐100.0) | 100.0 (99.2‐100.0) | ||||||||||||
| Kappa (95% CI) | 0.95 (0.90‐0.99) | 0.93 (0.87‐0.99) | 0.85 (0.69‐1.00) | 1.00 (1.00‐1.00) | 0.65 (0.46‐0.84) | 0.98 (0.95‐1.00) | ||||||||||||
| PABAK (95% CI) | 0.98 (0.96‐0.99) | 0.98 (0.96‐0.99) | 0.98 (0.97‐1.00) | 1.00 (1.00‐1.00) | 0.95 (0.92‐0.98) | 1.00 (0.99‐1.00) | ||||||||||||
Abbreviations: NPA, negative percent agreement; PABAK, prevalence and bias‐adjusted kappa; PPA, positive percent agreement; RSV, respiratory syncytial virus.