Table 1.
Top 10 biological processes identified by proteomic analysis in MCF-7 LTED cells compared to MCF-7 cells.
| Term | Count | % | p Value | Fold Enrichment | FDR |
|---|---|---|---|---|---|
| RNA processing | 188 | 7.75 | 1.80 × 10−31 | 2.33 | 3.35 × 10−28 |
| Establishment of protein localization | 235 | 9.69 | 1.47 × 10−30 | 2.07 | 2.73 × 10−27 |
| Protein transport | 233 | 9.60 | 2.45 × 10−30 | 2.07 | 4.56 × 10−27 |
| Translation | 133 | 5.48 | 8.43 × 10−30 | 2.72 | 1.57 × 10−26 |
| Protein localization | 255 | 10.51 | 4.90 × 10−29 | 1.96 | 9.13 × 10−26 |
| RNA splicing | 118 | 4.86 | 5.10 × 10−28 | 2.81 | 9.49 × 10−25 |
| mRNA metabolic processing | 138 | 5.69 | 4.41 × 10−27 | 2.53 | 8.20 × 10−24 |
| Intracellular transport | 203 | 8.38 | 4.87 × 10−27 | 2.09 | 9.07 × 10−24 |
| mRNA processing | 123 | 5.07 | 2.14 × 10−25 | 2.60 | 3.98 × 10−22 |
| Vesicle-mediated transport | 168 | 6.92 | 1.39 × 10−19 | 1.98 | 2.59 × 10−16 |
Differentially expressed proteins, determined by proteomic analysis, were analyzed to outline the most enriched biological processes. The table shows the top ten enriched terms that correspond to biological processes, along with the count of proteins involved, p value, fold enrichment and False Discovery Rate (FDR).