Table 2.
Hematological and Iron Indices before r-HuEPO and at PMA 35±1 wk
| N | Before EPO and High Iron Supplementation | PMA of 35 weeks | Mean Change (95% CI) | P-value | |
|---|---|---|---|---|---|
| Hematological Indices: | |||||
| Hemoglobin (gm/dL) | 104 | 14.1 ± 0.2 | 12.1 ± 0.1 | −2 (−2.5, −1.5) | <0.001 |
| Hematocrit (%) | 104 | 42.2 ± 0.5 | 38.4 ± 0.4 | −3.7 (−5.1, −2.4) | <0.001 |
| MCV (fL) | 104 | 113.6 ± 0.8 | 92.7 ± 0.5 | −20.8 (−22.3, −19.3) | <0.001 |
| Red Cell Width (RDW %) | 103 | 16.4 ± 0.2 | 23.6 ± 0.3 | 7.1 (6.5, 7.7) | <0.001 |
| Platelet Count (10^9/L) | 98 | 208.1 ± 6.3 | 278.4 ± 11.3 | 73.2 (50.2, 96.1) | <0.001 |
| Iron Indices: | |||||
| Serum Iron (mcg/dL) | 83 | 58.1 ± 2.7 | 87.9 ± 4.3 | 28.7 (17, 40.4) | <0.001 |
| Serum Ferritin (ng/mL) | 83 | 283.8 ± 15 | 107 ± 16.1 | −161.8 (−202.6, - | <0.001 |
| TIBC (mcg/dL) | 83 | 285.2 ± 4.8 | 333.2 ± 7.6 | 48.1 (28.2, 68) | <0.001 |
| Transferrin Saturation (%) | 83 | 20.7 ± 1 | 27.1 ± 1.3 | 6 (2.1, 9.8) | 0.003 |
| Transferrin (mg/dL) | 83 | 190.8 ± 3.2 | 223.6 ± 5.1 | 33.1 (19.8, 46.4) | <0.001 |
Mean ± SE, N at PMA 35wk