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. 2020 Jul 2;31(9):1996–2012. doi: 10.1681/ASN.2019111215

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Figure 4. — AREG induces myeloid cell–attracting chemokines and CSF2 secretion from resident renal cells. (A) Renal mRNA expression of the indicated chemokines at day 10 after NTN. (B) Expression of the indicated chemokine mRNAs by cultured mMC after stimulation with AREG and/or TNFα at the indicated concentrations in nanograms per milliliter. (C) Expression of the indicated chemokine mRNAs by cultured mPTC after stimulation with AREG and/or TNFα at the indicated concentrations in nanograms per milliliter. (D and E) Expression of CSF2 mRNA by cultured mMC and mPTC after stimulation with AREG, HB-EGF, or EGF in combination with TNFα at the indicated concentrations in nanograms per milliliter. Symbols represent individual animals or cell culture preparations, horizontal lines show mean values. **P<0.01; ***P<0.001. WT, wild-type.