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. 2020 Jun 26;31(9):2122–2132. doi: 10.1681/ASN.2020010038

Table 5.

Association of intensive BP target on cognitive impairment in baseline model, and with adjustment for baseline eGFR or postrandomization eGFR declines

eGFR, ml/min per 1.73 m2 HR (95% CI) for Intensive versus Standard
Probable Dementia MCI Probable Dementia or MCI
Original 0.83 (0.67 to 1.04) 0.81 (0.69 to 0.94) 0.85 (0.74 to 0.97)
Baseline eGFR <60 model 0.82 (0.66 to 1.03) 0.80 (0.69 to 0.94) 0.84 (0.74 to 0.96)
Decline in eGFR ≥30% model 0.85 (0.69 to 1.06) 0.84 (0.72 to 0.99) 0.88 (0.77 to 1.01)
Incident eGFR <60 model 0.84 (0.63 to 1.12) 0.73 (0.60 to 0.89) 0.80 (0.67 to 0.94)