Table 6.

Light microscopic pathologic findings of kidney tissues from ten deceased patients critically ill with COVID-19 and AKI

Patient	Sex/Age	PMH	Baseline sCr (μmol/L)	Peak sCr (μmol/L)	Disease Course (d)	Glomerular Changes	Tubulointerstitial Changes	Vascular Changes
1	M/62	HTN	N/A	427	33	Endothelial swollen	CV, focal TA and IF, crystallization casts, inflammatory cells infiltration	Intimal hyperplasia
2	M/82	DM	115	136	14	NR	CV, focal ATI	NR
3	M/62	–	73	220	29	NR	CV, focal ATI	Intimal hyperplasia
4	M/78	HTN	93	197	30	Focal ischemic sclerosis	CV, focal TA and IF	Intimal hyperplasia, hyalinosis
5	M/73	HTN, HBV	70	147	24	NR	CV, focal TA and IF, focal ATI	Intimal hyperplasia, venous thrombosis
6	M/59	HTN	48	139	39	Hypertrophy	CV, focal ATI	Intimal hyperplasia, hyalinosis
7	M/86	HTN, CAD	82	195	45	NR	CV, focal ATI	Intimal hyperplasia, hyalinosis
8	M/66	–	68	121	48	Focal ischemic sclerosis	CV, focal ATI, focal TA and IF	Intimal hyperplasia, hyalinosis
9	F/57	–	32	128	36	NR	CV, focal ATI	NR
10	F/66	DM	80	125	35	NR	CV, focal ATI	NR

M, male; PMH, past medical history; HTN, hypertension; DM, diabetes Mellitus; CAD, coronary artery disease; HBV, Hepatitis B virus infection; N/A, not available; CV, cytoplasmic vacuolization; TA, tubular atrophy, IF, interstitial fibrosis; NR, nonremarkable; ATI, acute tubular injuries; F, female.