Table 1:
Final Six Prioritized Variants associated with Longevity from the Six Cousin Pairs.
| Chromosome | Position in GRCh37 | Reference | Alternate | Accession Number | Gene Name | SIFT Function Prediction | Translation Impact |
|---|---|---|---|---|---|---|---|
| 5 | 102338739 | C | G | rs78408340 | PAM | Damaging | missense |
| 8 | 135614553 | G | C | rs112892337 | ZFAT | Damaging | missense |
| 12 | 53682043 | C | G | rs61737629 | ESPL1 | Damaging | missense |
| 14 | 23587838 | G | T | rs141903485 | CEBPE | Damaging | missense |
| 16 | 69170741 | G | T | rs144369314 | UTP4 | Tolerated | missense |
| 17 | 5289554 | T | C | rs61753103 | NUP88, RABEP1 | Tolerated | missense |
This table shows the results of the final Ingenuity Variant Analysis Biological Context Filter.