Skip to main content
. 2020 Aug 18;11:1757. doi: 10.3389/fimmu.2020.01757

Table 1.

The basic characteristics of two short pentraxins, CRP and SAP.

Characteristics CRP SAP
Genomic location 1q23.2 1q23.2
Gene sequence 1.8 kb in length, 0.1 kb of 5' UTR, 1.2 kb of 3' UTR 1.1 kb in length, 0.1 kb of 5' UTR, 0.15 kb of 3' UTR
Domain structures Pentraxin-related, ConA-like_dom_sf, Pentaxin_CS Pentraxin-related, ConA-like_dom_sf, Pentaxin_CS
Top tissue expression Liver Liver
Signaling pathway PI3K/Akt signaling pathway (25), JAK/STAT signaling pathway (35) PI3K/Akt/ERK signaling pathway (56)

CRP, C-reactive protein; SAP, serum amyloid P component; UTR, un-translated region; The domain structures were obtained from the Genecard database.