Table 1.
Demographic and clinical characteristics of the study population by hypothyroidism status (n = 3,703).
| Hypothyroidism (n = 251) n (%) | Without hypothyroidism (n = 3,452) n (%) | p-value | |
|---|---|---|---|
| Age (years ± SD) | 65.0 (± 16.9) | 56.4 (±18.2) | <0.001 |
| Female | 173 (68.9) | 1,481 (42.9) | <0.001 |
| Race | <0.001 | ||
| NHW | 114 (45.4) | 899 (26.0) | |
| NHB | 39 (15.5) | 953 (27.6) | |
| Other/ unknown | 98 (39.0) | 1,600 (46.4) | |
| Smoking | <0.001 | ||
| Never | 153 (61) | 1,991 (57.7) | |
| Former | 72 (28.7) | 641 (18.6) | |
| Current | 7 (2.8) | 186 (5.4) | |
| Unknown | 19 (7.6) | 634 (18.4) | |
| BMI | <0.001 | ||
| <25 | 74 (29.5) | 771 (22.3) | |
| 25-30 | 75 (29.9) | 981 (28.4) | |
| > 30 | 87 (34.7) | 985 (28.5) | |
| Unknown | 15 (6.0) | 715 (20.7) | |
| Number of Comorbidities* | <0.001 | ||
| 0 | 55 (21.9) | 1,305 (37.8) | |
| 1 | 52 (20.7) | 786 (22.8) | |
| 2 | 40 (15.9) | 575 (16.7) | |
| >2 | 104 (41.4) | 786 (22.8) | |
| Hospital admission | 171 (68.1) | 1,844 (53.4) | <0.001 |
NHB, Non-Hispanic Black; NHW, Non-Hispanic White; SD, standard deviation.
*
Comorbidities include hypertension, coronary artery disease, atrial fibrillation, congestive heart failure, peripheral vascular disease, cerebrovascular accident/ transient ischemic attack, dementia, diabetes, chronic kidney disease stage III or greater, malignancy (including all types of cancer as well as lymphoma and leukemia), asthma, chronic obstructive pulmonary disease and prior venous thromboembolism.