Figure 7.

E-cadherin immunofluorescent staining (×100) of a representative tumor section from the four groups at different time points. Bright red-stained E-cadherin was the most obvious in Group D in the late time points. Groups B and C also showed an increase of E-cadherin expression after treatment. The E-cadherin expression rapidly increased in both Groups B and D, especially in Group D, indicating more stable intercellular connectivity and lower likelihood of epithelial–mesenchymal transition after treatment. A mild increase was also observed in Group C, but a slow decline was observed in Group A.