TABLE 1.
Clinical variables of the 287 HNSCC patients with RT.
Variable | Subgroup | Total |
Training set |
Test set |
P* | |||
N | % | N | % | N | % | |||
Age (year) | ≤60 | 156 | 54.36 | 87 | 58.39 | 69 | 50.0 | 0.22 |
>60 | 131 | 45.64 | 62 | 41.61 | 69 | 50.0 | ||
Gender | Male | 224 | 78.05 | 123 | 82.55 | 101 | 73.19 | 0.15 |
Female | 63 | 21.95 | 26 | 17.45 | 37 | 26.81 | ||
T stage | 1 | 14 | 4.88 | 9 | 6.04 | 5 | 3.62 | 0.34 |
2 | 66 | 22.30 | 27 | 18.12 | 39 | 28.26 | ||
3 | 79 | 27.53 | 45 | 30.20 | 34 | 24.64 | ||
4 | 122 | 42.51 | 63 | 42.28 | 59 | 42.75 | ||
N stage | 0 | 113 | 39.37 | 57 | 38.26 | 56 | 40.58 | 0.35 |
1 | 56 | 19.51 | 26 | 17.45 | 30 | 21.74 | ||
2 | 105 | 36.59 | 59 | 39.60 | 46 | 33.33 | ||
3 | 3 | 1.05 | 0 | 0 | 3 | 2.26 | ||
Clinical stage | 1 | 9 | 3.14 | 2 | 1.34 | 7 | 5.07 | 0.30 |
2 | 23 | 8.01 | 12 | 8.05 | 11 | 7.97 | ||
3 | 48 | 16.72 | 21 | 14.09 | 27 | 19.57 | ||
4 | 207 | 72.13 | 114 | 76.51 | 93 | 67.39 | ||
Tumor grade | 1 | 25 | 8.71 | 11 | 7.38 | 14 | 10.14 | 0.20 |
2 | 168 | 58.54 | 82 | 55.03 | 86 | 62.32 | ||
3 | 75 | 26.13 | 47 | 31.54 | 28 | 20.29 | ||
4 | 2 | 0.70 | 2 | 1.34 | 0 | 0 | ||
Survival time (month) | 21.77 | 20.73 | 23.62 | 0.32 | ||||
Vital status | Death | 110 | 38.33 | 57 | 38.26 | 53 | 38.41 | 0.12 |
Alive | 177 | 61.67 | 92 | 61.74 | 85 | 61.59 |
* The difference between the test set and training set was calculated in terms of clinical pathologic factors. Specifically, age was compared with Wilcoxon rank-sum test; gender, clinical T, N, stage, and grade were compared with the chi-squared test; survival time and the status difference were assessed with the log-rank test.