Figure 1.
Shown are immune cell-derived molecules and tissue injury-derived molecules as well as the cells that they originate from. The molecules have various physiological functions and were described as biomarkers for acute GVHD. BAFF, B cell-activating factor; HGF, hepatocyte growth factor; IL, interleukin; REG3α, regenerating islet-derived protein 3α; sST2, soluble isoform of suppression of tumorigenicity 2; Th1 cells, T helper 1 cells; TNF-α, tumor necrosis factor α; TNFR1, tumor necrosis factor receptor 1; Tregs, regulatory T cells.