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. 2020 Aug 18;11:2063. doi: 10.3389/fimmu.2020.02063

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Copyright © 2020 Wang, Li, Yin, Zhang, Cao, Lin, Huang, Hoffmann, Lu and Qiu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome analysis of the lung and BALF in COVID-19 patient. (A) Marker genes from Microenvironment Cell Populations-counter (MCP-counter) were used to identify of Neutrophils, T cells, Monocytes, and B cells in both Lung and BALF samples of COVID-19 patients and healthy controls, respectively. The RNA-seq data TPM are shown in a scaled heatmap. (B) Circle plots for functional enrichment analysis of 29 marker genes of Neutrophils. (C) The absolute abundance of immune cell subpopulations as scores in COVID-19 patients and healthy cases.