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. 2020 Aug 18;10:1507. doi: 10.3389/fonc.2020.01507

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Copyright © 2020 Liu, Zhang, Liu, Sun, Guo, Tang, Wang, Li, He, Zhang, Wang, Li, Fan, Tsang, Zhang and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gender-dependent metabolomics/lipidomics characteristics. (A) Score plot of OPLS-DA model between females and males. Apparent separation of metabolomics was showed between males and females. (B) Pathway enrichment of gender-dependent metabolites and lipids. (C) Heat map showing the relative abundance of gender-dependent metabolites/lipids these performing important biological functions. (D) Highlighted pathways contain specific metabolites showing differences between the male and female. (A) Was created using simca 14.0; (B) Was created using MetaboAnalyst 3.0; (C) Was created using R package; (D) Was created using Microsoft office PPT 2007.