Table 2.
Influence of fibrillar collagen expression on cancer properties.
| Type | Subtype | Cancers | Implications | References |
|---|---|---|---|---|
| COL I | COL1A1 | Hepatocellular | Clonogenicity, motility, invasiveness and stemness | (149) |
| Bladder | Proliferation, migration, and invasion | (150) | ||
| Malignant astrocytoma | Invasion | (151) | ||
| Breast | Migration | (152) | ||
| Colorectal | Migration | (153) | ||
| Oral squamous cell carcinoma | Proliferation and migration | (154) | ||
| Gastric | Proliferation, migration, and invasion | (155) | ||
| COL II | COL2A1 | Ovarian | Prognostic value | (156) |
| Gastric | Prognostic value | (157) | ||
| Biomarker | (158) | |||
| COL III | COL3A1 | Ovarian | Lymphovascular metastasis | (159) |
| Patient survival | (160) | |||
| Drug resistance | (161) | |||
| Bladder | Patient survival | (162) | ||
| Glioblastoma | Patient survival | (163) | ||
| Colorectal | Patient survival | (164) | ||
| Proliferation | (164) | |||
| COL V | COL5A1 | Ovarian | Lymphovascular metastasis | (159) |
| Breast | Viability and migration | (165) | ||
| Patient survival | (165) | |||
| Lung | Proliferation, apoptosis, invasion | (166) | ||
| Patient survival | (166) | |||
| Renal | Proliferation, apoptosis, migration, invasion | (167) | ||
| Patient survival | (167) | |||
| Tongue squamous cell carcinoma | Patient survival and metastasis | (168) | ||
| Breast | Prognostic value | (169) | ||
| COL5A2 | Ovarian | Lymphovascular metastasis | (159) | |
| Tongue squamous cell carcinoma | Patient survival | (168) | ||
| Bladder | Patient survival | (170) | ||
| COL5A3 | Breast | Proliferation | (171) | |
| COL XI | COL11A1 | Ovarian | Patient survival | (172) |
| Invasion | (172) | |||
| Drug resistance | (173) | |||
| Non-small cell lung carcinoma | Proliferation, migration, invasion, drug resistance | (174) | ||
| Pan-cancer | Marker of activated CAF | (175) | ||
| Gastric | Proliferation, migration, invasion | (176) | ||
| Esophageal squamous cell carcinoma | Prognostic value | (177) | ||
| Pancreas | Prognostic value | (178) | ||
| Breast | Prognostic value | (179) | ||
| COL XXIV | COL24A1 | Head and neck | Prognostic value | (180) |
| Hepatocellular carcinoma | Prognostic value | (181) |