Table 3.

Specificity of collagen-binding integrins.

Integrin subunit	Collagen specificity	Motifs	Other ECM ligands	References
α1	Collagen I, II, III, IV, V, VI, IX, XVI and XVIII Highest affinity for collagen IV	GFOGER (collagen I, II, IV) GVOGEA (collagen II) GLOGEN (collagen III)	Laminins, galectins, arresten and semaphorin 7A	(231–233, 237, 238)
α2	Collagen I, II, III, IV, V and XI	GFOGER (collagen I, II, IV) GMOGER	Laminins, Tenascin C, decorin, endorepellin, perlecan, and chondroadherin	(231–233, 239, 240)
α10	Collagen I, II, IV, VI Highest affinity for collagen IV and VI	GFOGER (Collagen I, II, IV)	ND	(233, 236, 241)
α11	Collagen I, IV, V, IX Highest for collagen I	GFOGER (Collagen I, II, IV)	ND	(231, 232, 242, 243)