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. 2020 Aug 18;10:1372. doi: 10.3389/fonc.2020.01372

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Copyright © 2020 Wei, Chen, Qin, Guo, Zhu, Li, Min and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The diagnostic performance of circulating EV-miR-193a-5p as biomarkers in colorectal cancer (CRC). (A) Evaluation of EV-miR-193a-5p as a predictive biomarker in CRC vs. colorectal adenoma (CA)+non-cancerous control (NC), and CRC+CA vs. NC. (B) Evaluation of EV-miR-193a-5p as a predictive biomarker in CRC vs. CA, CRC vs. NC, and stage II/III CRC vs. NC. (C) Comparison between EV-miR-193a-5p and the model-integrated EV-miR-193a-5p and age in predicting CRC from CA+NC. (D) Comparison between EV-miR-193a-5p and the model-integrated EV-miR-193a-5p and age in predicting CRC from NC.