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. 2020 Aug 18;10:1459. doi: 10.3389/fonc.2020.01459

Table 1.

Relationship between clinical characteristics and Fibrinogen–Albumin Ratio Index.

Variables Total (n = 357) FARI-low (n = 243) FARI-high (n = 114) χ2 P-value
Gender 0.795 0.373
Male (%) 185 (51.8) 122 (50.2) 63 (55.3)
Female (%) 172 (48.2) 121 (49.8) 51 (44.7)
ECOG score 3.621 0.164
0 (%) 267 (74.8) 189 (77.8) 78 (68.4)
1 (%) 78 (21.8) 47 (19.3) 31 (27.2)
2 (%) 12 (3.4) 7 (2.9) 5 (4.4)
Age, years 60.88 ± 12.05 59.47 ± 12.56 62.82 ± 10.72 −2.466 0.014
BMI (kg/m2) 0.533 0.465
<18.5 (%) 15 (4.2) 12 (4.9) 3 (2.6)
≥18.5 (%) 342 (95.8) 231 (95.1) 111 (97.4)
Tumor size 32.394 <0.001
≤ 2 (%) 82 (22.9) 67 (27.6) 15 (13.1)
>2, ≤ 5 (%) 142 (39.8) 105 (43.2) 37 (32.6)
>5, ≤ 10 (%) 80 (22.4) 51 (21.0) 29 (25.4)
>10 (%) 53 (14.9) 20 (8.2) 33 (28.9)
Tumor location 4.126 0.248
stomach (%) 221 (61.9) 158 (65.0) 63 (55.3)
Intestine (%) 75 (21.0) 45 (18.5) 30 (26.3)
Colorectum (%) 27 (7.6) 19 (7.8) 8 (7.0)
E-GIST (%) 34 (9.5) 21 (8.7) 13 (11.4)
Mitotic index (per 50 HPF) 10.462 0.005
≤ 5 (%) 211 (59.1) 157 (64.6) 54 (47.4)
>5, ≤ 10 (%) 60 (16.8) 38 (15.6) 22 (19.3)
>10 (%) 86 (24.1) 48 (19.8) 38 (33.3)
NIH risk category 22.978 <0.001
Very low (%) 64 (17.9) 54 (22.2) 10 (8.8)
Low (%) 101 (28.3) 75 (30.9) 26 (22.8)
Intermediate (%) 61 (17.1) 44 (18.1) 17 (14.9)
High (%) 131 (36.7) 70 (28.8) 61 (53.5)
Surgery 15.342 <0.001
Open (%) 184 (51.5) 108 (44.4) 76 (66.7)
Laparoscopy (%) 173 (48.5) 135 (55.6) 38 (33.3)
Clavien–Dindo grade 0.009 0.925
<3 (%) 314 (88.0) 214 (88.1) 100 (87.7)
≥3 (%) 43 (12.0) 29 (11.9) 14 (12.3)
NLR 6.111 0.013
Low (%) 96 (26.9) 75 (30.9) 21 (18.4)
High(%) 261 (73.1) 168 (69.1) 93 (81.6)
PLR 15.270 <0.001
Low (%) 147 (41.2) 117 (48.1) 30 (26.3)
High (%) 210 (58.8) 126 (51.9) 84 (73.7)
PNI 38.956 <0.001
Low (%) 147 (41.2) 73 (30.0) 74 (64.9)
High (%) 210 (58.8) 170 (70.0) 40 (35.1)

FARI, fibrinogen–albumin ratio index; ECOG, Eastern Cooperative Oncology Group; BMI, body mass index; NIH, National Institute of Health; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index.