Table 1.

Analysis of the multidrug efflux pump encoding genes present in the adherent-invasive Escherichia coli (AIEC) LF82 genome.

Family	MG1655	LF82	DNA Sequence homology (%)*	Protein homology (%)*
ABC	macAB	+	98.17	98.65; 99.38
MFS	bcr	+	96.81	99.49
	emrAB	+	98.06	99.74; 99.80
	emrD	+	97.81	99.49
	emrKY	+	97.41	98.19; 100
	fsr	+	97.87	99.75
	mdfA	+	98.05	100
	mdtG	+	98.45	99.51
	mdtH	+	98.35	100
	mdtL	+	96.51	98.47
	mdtM	−	−	−
RND	acrAB	+	98.81	99.75; 100
	acrD	+	98.5	99.81
	acrEF	+	97.26	98.96; 99.52
	cusB	+	97.3	98.77
	mdtABC	+	95.35	98.80; 99.71; 98.83
	mdtEF	+	97.72	99.74; 99.42
SMR	emrE	+	98.8	99.09
	mdtJI	+	98.53	100; 100
MATE	mdtK	+	97.82	99.78

The 20 genetic systems encoding functional efflux pumps in Escherichia coli have been selected according to Nishino and Yamaguchi (2001). The comparative analysis between the genome of E. coli K-12 and AIEC LF82 strain was carried out using NCBI BLAST (http://blast.ncbi.nlm.nih.gov/Blast.cgi). The nucleotide sequences of each efflux pump encoding gene were obtained from EcoCyc (https://ecocyc.org).

+ Efflux pump encoding genes present in the LF82 genome. − Not present in the LF82 genome.

^*Sequence and amino acid homology expressed as a percentage.