Table 2.

Relationship Between Clinical Characteristics and Gene Expression of PDZ-Binding Kinase in the HOVON-65/GMMG-HD4 Clinical Trial

		N	PBK gene expression (Log2 value)						P
			Low	%	High	%	Ave.	SD
Total		290	228	78.6	62	21.4	6.40	1.44
ISS	I	114	98	86.0	16	14.0	6.10	1.36
	II	71	52	73.2	19	26.8	6.61	1.34	0.047 (versus I)
	III	78	56	71.8	22	28.2	6.70	1.53	0.011 (versus I)
	NA	27	22	81.5	5	18.5	6.23	1.56

PBK expression low, log₂ <7.5; PBK expression high, log₂ >7.5. The statistical analysis was performed using one-way ANOVA with pairwise comparison (Turkey).

ANOVA, analysis of variance; ISS, International Staging System; NA, not analyzed; PBK, PDZ-binding kinase; SD, standard deviation.