Fig. 3.

Influence of EDCs across the lifespan. EDCs and other environmental toxicants are an important component of the overall environmental milieu (blue) that interacts with genetic susceptibility to influence diabetes pathogenesis across the lifespan (green arrow). Importantly, exposures during sensitive windows can disrupt developmental programming and result in long-term metabolic dysfunction in both the exposed individual as well as future generations (black arrows). This figure is available as part of a downloadable slideset