Figure 1:

Schematic of study design. A) Three regions of porcine airway were evaluated, including trachea, large bronchi, and small bronchi. B) For each region, samples were orientated along the circumferential or axial direction, with fibers aligned along the axial direction. C) The stress-strain response was curve-fit to a structure-based constitutive model that included a description for the fibers and extrafibrillar matrix. D) Methods for model selection, whereby circumferential samples informed the matrix model, which was combined with a fiber model to fit axial samples.