Table 5.
Treatment-Related Serious Adverse Effect Reported in 40 Cancer Survivors Treated With GH for GH Deficiency
| Category | Diagnosis | No. of Patients |
|---|---|---|
| General and metabolic | Fatigue | 1 |
| Type 1 diabetes mellitus | 2 | |
| Type 2 diabetes mellitus | 1 | |
| Musculoskeletal | Muscle spasm | 1 |
| Scoliosis | 3 | |
| Hip epiphysiolysis | 1 | |
| Peripheral edema | 1 | |
| Neurologic | Headaches | 4 |
| Epilepsy | 2 | |
| Tumor | PNET progression | 1 |
| Recurrence of craniopharyngioma | 20 | |
| Recurrence of Ewing sarcoma | 1 | |
| Recurrence of optic glioma | 3 (1 death) |
Abbreviation: PNET, primative neuroectodermal tumor.