Table 3.

Respiratory variables on Days 1 and 3 between those who remain intubated, those extubated, and those who died

Variables	Currently Intubated	Extubated	Deceased	P Value^*	q Value^†
Day 1	n = 141^‡	n = 77^‡	n = 49^‡
Pa_CO₂	44 (38–53)	43 (38–49)	46 (38–53)	0.3	0.8
Pa_O₂:Fi_O₂	105 (81–130)	104 (85–139)	98 (81–133)	0.4	0.8
Tidal volume/predicted weight, cc/kg	7.03 (6.23–8.10)	7.06 (6.17–8.24)	6.30 (5.95–7.57)	0.2	0.8
Static compliance, cm H₂O	28 (20–39)	29 (23–40)	29 (24–37)	0.5	0.8
Driving pressure, cm H₂O	14.0 (11.0–17.8)	13.0 (9.0–16.5)	15.0 (12.0–18.0)	0.3	0.8
Plateau pressure, cm H₂O	26.0 (22.0–29.0)	24.0 (20.0–28.0)	26.0 (22.0–30.0)	0.4	0.8
PEEP, cm H₂O	10.0 (10.0–12.0)	10.0 (8.0–12.0)	10.0 (8.5–10.0)	0.3	0.8
Exhaled minute volume, L/min	9.45 (8.09–11.45)	9.30 (8.10–10.85)	9.95 (8.33–11.38)	0.8	0.9
Ventilatory ratio	1.83 (1.51–2.32)	1.76 (1.45–2.18)	1.82 (1.44–2.58)	0.6	0.8
Day 3	n = 131^‡	n = 73^‡	n = 43^‡
Pa_CO₂	48 (42–52)	46 (40–50)	47 (41–52)	0.4	0.5
Pa_O₂:Fi_O₂	136 (106–168)	153 (122–192)	129 (107–156)	0.028	0.086
Tidal volume/predicted weight, cc/kg	6.43 (6.01–7.01)	6.30 (6.00–6.84)	6.35 (5.97–6.96)	0.6	0.6
Static compliance, cm H₂O	30 (24–42)	31 (26–38)	35 (26–44)	0.2	0.3
Driving pressure, cm H₂O	13.0 (10.0–16.0)	12.0 (9.0–14.2)	12.0 (8.5–15.0)	0.4	0.5
Plateau pressure, cm H₂O	25 (22–28)	23 (19–26)	25 (20–28)	0.090	0.2
PEEP, cm H₂O	12.0 (10.0–14.0)	10.0 (8.0–14.0)	12.0 (10.0–14.0)	0.021	0.086
Exhaled minute volume, L/min	10.20 (8.68–11.85)	9.00 (8.08–10.00)	11.40 (10.00–12.50)	<0.001	<0.001
Ventilatory ratio	1.97 (1.63–2.50)	1.79 (1.48–2.12)	2.26 (1.53–2.50)	0.036	0.086

Definition of abbreviations: Fi_O₂ = fraction of inspired oxygen; Pa_CO₂ = arterial carbon dioxide pressure; Pa_O₂ = arterial oxygen pressure; PEEP = positive end-expiratory pressure.

Statistical test: Kruskal-Wallis.

^{^†}

False discovery rate correction for multiple testing.

^{^‡}

Data presented as median (interquartile range).