Table 1.
Baseline characteristics of all participants, including children with PCD, children with CF, and healthy control subjects*
| Characteristics | Subjects with PCD (n = 25) | Subjects with CF (n = 49) | HC Subjects (n = 80) |
|---|---|---|---|
| Sex, M, n (%) | 13 (52) | 26 (53%) | 37 (46) |
| Age, median (IQR), yr | 8.6 (5.9 to 10.0) | 8.9 (6.8 to 10.8) | 8.6 (6.0 to 10.9) |
| Weight z-score†, median (IQR) | −0.34 (−1.01 to 0.53) | −0.30 (−0.67 to 0.50) | 0.21 (−0.51 to 0.89) |
| Height z-score†, median (IQR) | −0.53 (−1.18 to 0.31) | −0.27 (−1.02 to 0.25) | −0.02 (−0.67 to 0.62) |
| BMI z-score†, median (IQR) | −0.08 (−0.78 to 0.93) | 0.13 (−0.45 to 0.73) | 0.41 (−0.30 to 0.93) |
| Race/ethnicity, n (%) | |||
| White, non-Hispanic | 23 (92) | 46 (94) | 60 (75) |
| Black | 0 (0) | 1 (2) | 6 (7) |
| Asian | 0 (0) | 0 (0) | 3 (4) |
| Hispanic | 2 (8) | 2 (4) | 8 (10) |
| Other | 0 (0) | 0 (0) | 3 (4) |
| Acceptable MBW | 18 (72) | 37 (76) | 60 (75) |
| Acceptable spirometry | 23 (92) | 47 (96) | 73 (91) |
Definition of abbreviations: BMI = body mass index; CF = cystic fibrosis; HC = healthy control; IQR = interquartile range; MBW = multiple breath washout; PCD = primary ciliary dyskinesia.
*
The initial cohort included 45 historical study participants.
†
Calculated using Centers for Disease Control and Prevention reference data.