Table 2:
Medical history of DICER1-carrier women with Ovarian Sertoli Leydig cell tumors
Patient | Age at Menarche (yrs) | Age at Tumor (yrs) | Surgical Treatment | Pathology Report | Chemotherapy |
---|---|---|---|---|---|
1: 114–1 | 13 | 8 | 1st: Left oophorectomy, omentectomy | Sertoli-Leydig cell tumor, retiform variant | No |
14 | 2nd: Right salpingo-oophorectomy | Sertoli-Leydig cell tumor of intermediate differentiation | No | ||
2: 151–1 | 14 | 13 | Left salpingo-oophorectomy | Sertoli-Leydig cell tumor of intermediate differentiation | Yes |
3: 145–4 | 11 | 14 | 1st: Right salpingo-oophorectomy | Unavailable, but mother said tumor had hair and teeth, suggesting dermoid cyst | No |
60 | 2nd: Left salpingo-oophorectomy | Sertoli-Leydig cell tumor of intermediate differentiation | Yes | ||
4: 151–2 | 16 | 16 | Left salpingo-oophorectomy | Unavailable, but menses resumed after oophorectomy | No |
5: 135–1 | 11 | 16 | Right salpingo-oophorectomy | Gynandroblastoma | No |
6: 135–2 | 11 | 16 | Right salpingo-oophorectomy | Gynandroblastoma | Yes |
7: 168–1 | 13 | 17 | Right oophorectomy | Sertoli-Leydig cell tumor of intermediate differentiation | No |
8: 141–1 | 14 | 18 | Right salpingo-oophorectomy | Sertoli-Leydig cell tumor of intermediate differentiation | No |
9: 133–1 | 12 | 40 | 1st: Left salpingo-oophorectomy | Sertoli-Leydig cell tumor of intermediate differentiation | No |
40 | 2nd: Second surgery 3 months later; laparoscopic hysterectomy, Right salpingo-oophorectomy | Carcinoid tumor | No |