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. 2020 Jul 14:bbaa141. doi: 10.1093/bib/bbaa141

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© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

A stepwise workflow showed the combined antiviral activity of VC and GA against COVID-19 through network pharmacology. We identified candidate biotargets of VC and GA, then determined and mapped their combined core biotargets against COVID-19. A PPI diagram of VC + GA against COVID-19 was generated. Our analysis revealed the pharmacological functions and molecular pathways of VC + GA action against COVID-19.