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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Nat Catal. 2019 Aug 12;2(9):756–762. doi: 10.1038/s41929-019-0330-7

Fig. 2. Aminating agent and C–H bond substrate scope for α-branched amine synthesis.

Fig. 2.

Reactions were performed on 0.3 mmol scale at [0.2 M] with respect to C–H bond substrates. Ratio of C–H bond substrate: aminating agent: alkene (1:1.5:2). One equivalent of NaHCO3 was used as an additive for oxime C–H bond substrates and one equivalent of pivalic acid (PivOH) was used as an additive for triazole and amide C–H bond substrates. Isolated yields of product after purification by chromatography are reported. See Supplementary Methods for experimental details. a Reactions performed with 1 mol % of [Cp*RhCl2]2 and 4 mol % of AgSbF6. b Reactions performed at 70 °C.