Table 4:

Results of linear regression models predicting cycle threshold (Ct) value from the HIV diagnostic total nucleic acid PCR test

	Univariate Each covariate on their own predicting Ct In whole population (N=316)			Multivariable All covariates shown entered simultaneously into a model predicting Ct In those VL <50 copies/mL at time of test (N=288)			Multivariable All covariates shown entered simultaneously into a model predicting Ct In ESRU only and VL <50 copies/mL at time of test (N=211)
	Parameter estimate	Standard error	p-value	Parameter estimate	Standard error	p-value	Parameter estimate	Standard error	p-value
Age at ART start (months)	−0.106	0.018	<0.0001	−0.115	0.018	<0.0001	−0.104	0.018	<0.0001
VL sustained <400 copies/mL during CHANGES (Yes vs. No)	1.804	0.214	<0.0001	1.572	0.227	<0.0001	1.371	0.241	<0.0001
Ever treated with EFV (Yes vs. No)	0.633	0.235	0.007	0.563	0.238	0.019	0.576	0.294	0.051
CD4+ T-cell count (cells/mm3) at PCR test (divided by 100)	−0.029	0.037	0.426	−0.104	0.038	0.006	−0.098	0.038	0.010
Site (ESRU vs. PHRU)	0.403	0.265	0.130	0.504	0.264	0.057	-	-	-
VL <50 copies/mL at test	2.345	0.387	<0.0001	-	-	-	-	-	-