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ACE2 (angiotensin-converting enzyme 2) is overexpressed in human rhinovirus (RV)-infected human nasal tissue cultures. ACE2 fold change of expression varies from 3.2 to 3.6 in the discovery and validation cohorts after RV-A and RV-C infection. TMPRSS2 is not reproducibly altered by RV infections. The mRNA expression was calculated by normalization of voom counts. n.s. = not significant; TMPRSS2 = transmembrane serine protease 2.
