Table 1.
Clinical and Laboratory Characterization
| Demographics and Clinical Characteristics | Number (%), Median (Range), or Mean (±SD) |
|---|---|
| Age | 52.5 (29–79) |
| Sex, M | 32 (82) |
| Sex, F | 7 (18) |
| White | 14 (36) |
| Black and minority ethnic | 25 (64) |
| BMI, kg/m2 | 31.3 (±6.1) |
| BMI > 30 kg/m2 | 22 (57) |
| Diabetes mellitus | 8 (21) |
| Hypertension | 15 (39) |
| Asthma | 3 (8) |
| Hyperlipidemia | 2 (5) |
| Physiologic characteristics (on admission) | |
| PaO2/FiO2 | 114.9 (±74.2) |
| PaCO2, mm Hg | 63.6 (±20.6) |
| Minute ventilation, L/min | 11.7 (±2.2) |
| Dynamic compliance, ml/cm H2O | 33.7 (±14.7) |
| Positive end-expiratory pressure, cm H2O | 12.3 (±2.4) |
| Murray lung injury score | 3.14 (±0.53) |
| Ventilatory ratio | 2.6 (±0.8) |
| Admission sequential organ failure score | 8.0 (±2.5) |
| Admission APACHE II score | 18.7 (±5.0) |
| Respiratory ECMO survival prediction score | 3.4 (±1.9) |
| Laboratory tests on admission (normal values) | |
| White cell count, ×109/L (3.6–11.0) | 10.6 (±4.4) |
| Neutrophils, ×109/L (1.8–7.5) | 9.3 (±4.3) |
| Lymphocytes, ×109/L (1.0–4.0) | 0.76 (±0.4) |
| Creatinine, μmol/L (45–110) | 172 (±141) |
| CRP, mg/L (<3) | 305 (±101) |
| Ferritin, ng/ml (18–270) | 987 (552–1,425) |
| Lactate dehydrogenase, U/L (<250) | 996 (773–1,270) |
| Platelets, 109/L (146–360) | 272 (±77) |
| Fibrinogen, g/L (1.5–4.5) | 6.6 (±1.9) |
| Antithrombin 3, IU/dl (70–140) | 70.6 (±23.7) |
| APTT, s (26–36) | 38.8 (±13.1) |
| PT, s (10–12.5) | 14.1 (±2.1) |
| D-dimer, ng/ml (208–318) | 6,440 (±10,434) |
| High-sensitivity troponin, ng/L (<14) | 143 (±262) |
| Brain natriuretic peptide, ng/L (<100) | 186 (±274) |
Definition of abbreviations: APACHE = The Acute Physiology and Chronic Health Evaluation; APTT = activated partial thromboplastin time; BMI = body mass index; CRP = C-reactive protein; ECMO = extracorporeal membrane oxygenation; PT = prothrombin time.